Well, actually, ISO may be a little better, since it’s easier not to screw up the burning process. But content-wise, definitely the same thing.
I haven’t been paying attention to the BD projects here in this thread but thought I should mention that if you have integrated (real) seamless branching somewhere on the disc then it is imperative that you burn from the disc image in order to maintain the physical disc layout and prevent skipping during playback of the branches. With the right authoring software it will interleave the 2 branches so that they occupy a similar space on the disc to prevent the laser from having to bounce around. Otherwise, yeah, about the same thing.
True. LBA matters for these kind of things. But it doesn’t really matter as far as homebrew discs go. Not a single member here has gotten seamless branching working successfully on a blu-ray disc. Or, if they have, they have kept it to themselves.