Unfortunately there’s really not much doubt about the dislike of the Ghostbusters trailer being due at least in part to misogyny.
Beloved movies/franchises getting reboot/remakes are far from something new (and neither are bad trailers). The volume here is telling (not to mention the comments).
The trailer is being received so poorly because it’s bad.
Ghostbusters is a beloved franchise and they released a trailer for a remake that frankly, isn’t funny and has some very bad SFX; when the monster effects from the original look better you know you’re doing something wrong.
It has nothing to do with women being in the lead, like another poster said, the TFA trailer wasn’t annihilated by fans for having a woman in the lead, it was universally loved.
While I think TFA is a pile of crap I don’t dislike it because the lead is a woman, I hate it because I don’t think it’s a good film.
Clearly lots of people think that Ghostbusters just does not look like a good film.
The main complaint is that this comedy film is not funny, not that the leads have vaginas.
Stop using buzzwords as a scapegoat, they don’t help your argument and they don’t hold up to scrutiny.