I will have said it before and I will say it again. The MCU is really lacking female characters with Super powers who get their own movies, that combined with the fact that I don't want to see the origin story yet again leads me to have this be my dream project, Spider-Girl coming into the MCU.

Have Peter in the movies played by an older actor who got his powers and was a hero in the 70s, he could still be involved in the plots doing science and research stuff while Mayday could have decided to go out there and help save the city after it was attacked in The Avengers. This would explain why we have not heard of Spiderman in the MCU up until know and we wouldn't be forced to sit through the origin yet again.

Plus they could give Peter flashbacks to when he was a hero in the 70s and 80s, so we could still see him in action. I know this will never happen in real life but it's my dream Spiderman film project.