TheHutt said:

I doubt you can split a film with frame precision in TSmuxer.

You can't split with single frame precision with TSmuxer but in this case I don't believe you need to. I don't know about Andrea's workflow but in his place I would split the film as close as I could to the flaw and start encoding from the next frame after the first part of the split ends to the end of the film, then use tsmuxer to join the first part of the split to the new corrected encode of the last five minutes, saving myself having to reencode the whole film in the process.