Really looking forward to Bioshock: Infinite (and I'm so glad they decided to include reversible box art) and The Last of Us. I think those are going to be my two launch day purchases for the year.
And I'd still really like to play Borderlands 2 and Far Cry 3 eventually.
I'm thinking about catching up on the God of War series while I wait for Bioshock. I have still never beaten God of War 2, and have yet to play 3, but I have them all, including the origins collection.