I go out for the evening, and people start getting cranky with each other, sheesh. I still have a he who shall not be named hangover. ;)
I don't think it's possible to avoid reference to anything from the prequels the way the rest of the Star Trek films essentially ignored the events of TMP. Coruscant is the hub of the Galaxy, unless events take the plot far from there.
Whatever government the Rebellion formed post Jedi would probably want to set up shop there. I would hope that for the most part, the sequels take us to new worlds we haven't seen before on screen.