I basically just consider the prequels to be glorified EU material. You can take them or leave them but at the end of the day, the originals are all that really matter. The originals can exist without the prequels, it doesn't doesn't work the other way around.
I've never read a single EU book other than the Episode 2 novelization, Shadows of the Empire, and some comics, but I accept the details as canon. That's how I view the prequels and the Clone Wars.