I gravitate towards independents: and at this point i'm only remembering b/w titles... odd
'Cursed Pirate Girl' by Jeremy Bastian
Review: http://robot6.comicbookresources.com/2009/09/gorillas-riding-dinosaurs-cursed-pirate-girl-1-2/
(view the below image at full resolution: awesome http://robot6.comicbookresources.com/wp-content/uploads/2009/09/cpg_3omerta.jpg )
Publisher website: http://www.olympianpublishing.com/store/index.php
Paul Pope's THB should be returning in some form, hopefully really soon. Anything by the guy is great.
'Breathers' by Justin Madson (http://www.justmadbooks.com/)
after being self published in an odd size/format. the series has been put out ina collected volume.
If you haven't read anything by Masamune Shirow (Ghost in the Shell) worth a try.
http://en.wikipedia.org/wiki/Masamune_Shirow
If you want a weird experiential book, anything by Tsutomu Nihei. Biomega is currently getting an english translation and Blame! is already done.
http://en.wikipedia.org/wiki/Tsutomu_Nihei
'Eden - It's an Endless World' by Hiroki Endo
political theater, the world is plagued by a new crystalline virus. nations dissolve and reform, new organizations spring up. Story follows the son of a major player.
http://en.wikipedia.org/wiki/Eden:_It%27s_an_Endless_World!
'Nightly News' by Jonathan Hickman
A cassette tape (the Voice) is telling people to kill news reporters.
http://en.wikipedia.org/wiki/The_Nightly_News
Then there's more humorous stuff, josei manga, korean manwha. lots to chose from.
Comics are finally getting digital releases too, so when you find a title you like see if the author is directly selling it.