005/C3PX:
Did you ever read/hear about Irrational's cancelled zombie game (before BioShock, before L4D)?
It sounded pretty cool. Imagine L4D, but with a strategic element. It was all based on the idea that you were hunkered down in this fort, but you had to go out for supplies. Or to save survivors. Or to restore power to your building so the electrified fence worked. Or whatever.
Maybe Xcom is a better comparison.
It actually sounded pretty cool to me- I'd like a little of that mixed in with my L4D.