CP3S said:

Haha, so I sat down to play Assassin's Creed II and there is no voice audio

Finding absolutely nothing helpful online. Well, I guess that is the end of Assassin's Creed II for me.

EDIT: Well, spent even more time searching and I am officially giving up.

Soooo, hopefully I can at least get a few bucks for this POS game by selling it on amazon.

Wow, that really sucks.

What kind of audio set-up are you using? Digital from Xbox to TV/Receiver or analogue? Have you tried using whichever one you're not using? Have you tried changing your audio out settings on the xbox itself?

Have you tried not pirating the game?