BioShock- I'd like to see if it could be done and I'd love to see the world visualized even a little more realistically than the game... though I have strong doubts as to whether they could condense the story into a movie. Also, the 'free roaming', "you are in Rapture" element of the game is one of the more compelling aspects that I think would never translate to film.

I think the Dresden files series would work very well as movies. There was a SciFi TV show that was relatively well done, but the budget constrained the fantasy elements of the show and I think the increased timeline (40 mins -> 2 hours) would give it some weight as well.

I'd love to see a movie version of the X-Men comic Inferno. But done faithfully. I'm kind of surprised that Marvel and DC haven't started litterally adapting several of their more important/popular stories as animated features. This would give them the ability to do faithful translations with fewer concerns- like famous actors getting enough screen time without their masks, etc. But the Planet Hulk movie was disappointing... I'm not sure how they condensed 15-odd issues into a 70 minute movie. I have a friend near animation and he says that every frame that can be dropped means substantial cost savings to the producers. However, I don't see the point of doing it unless it's "good" and I don't think it was good at 70 minutes. 2ish hours, or don't do it at all.