In ANH, Obi-Wan tells Luke that Owen feared that Luke "Might follow old Obi-Wan off on some damn fool idealistic crusade like your father did"
This is inconsistent with the characters of Obi-Wan and Anakin in Eps I and II. Obi-Wan is sensible and responsible, whereas Anakin is the reckless one. Which one of the two is more likely to want to go off on "some damn fool idealistic crusade"? - Certainly not Obi-Wan.
I wonder if Episode III will explain what the "damn fool idealistic crusade" was? Whatever the Obi-Wan of the PT chooses to fight for, he takes it far too seriously to disparage it as "damn fool idealistic". Or maybe, by the time of ANH he has become old and cynical. Perhaps by that time he thinks that the whole idea of fighting for the lost Republic and saving the Galaxy from the Dark Side was all one big lost cause, so he writes off the whole enterprise as just "some damn fool idealistic crusade" which had not chance of success.
Another potential plot hole also appears in the same scene in ANH when Obi-Wan tells Luke that Owen thought Luke's father "should have stayed here (on Tattooine) and not gotten involved". For it to be a correct account of Luke's father's life, Episode III will have to involved Anakin once again returning to his home planet of Tattooine and Owen: (a) trying to exert influence over Anakin; and (b) expressing a political opinion. Neither of these actions seem very likely from the meek and quiet Owen we see in Episode II.