Well, if you consider The Bible to be "real", then it did have the power to instantly kill anyone who touched it, as referenced in C3PX's post. If you don't believe it to be "real," then, no, it's just a story about a box that has similar powers in both The Bible and in Raiders.
Oh, and I loved that Casablanca story, C3PX, as well as your new and improved Indy titles.