Mother beat me to it! Yeah, you don't want to risk losing detail in the white or dark areas so you need to check your settings/captures for each project. In fact (although rare) there can occasions where one section of a film will need to have a different brightness setting than another part of that same film! And make sure your monitor is calibrated to at least some degree before all this of course (I know a lot of us can't afford a pro calibration; at least I can't).