Generally a large file like a full-length film will need to packed into a split-volume RAR archive, and the volumes uploaded separately.
The two sites I think are the most popular are rapidshare and megaupload. For downloaders, Rapidshare asks you to identify cats and dogs and type some text, while Megaupload gets you to wait 40 seconds and view some ads about women who live in your town looking for a date.
For private sharing, you'd be much better off setting up an ftp server.