I don't have any special set-up myself, but a DVD cover is smaller in both dimensions than a piece of A4 paper. My box art would probably be too wide, but there are always ways. The trick is to get it to print at the right size, and I have no idea how to do this — I haven't printed out any of my covers yet — so I just worked to the same resolution scale as Sky_'s Revisited cover for all of mine.