European Portuguese (which is basically, well, from Portugal) have some differences on how words are spelled, the way some verbs are conjugated (not gramatically, but the use of those verbs), and a very distinct vocabulary. The accent is so much different that sometimes it gets hard to understand what a portuguese is saying. Brazillian portuguese is spoken in a more clear, well pronounced manner, while in portugal sometimes vowels have different sounds ("a" sounds like "oo" and "e" sounds like "ah" in parabéns - congratulations) parts of a word are not pronounced at all.

Portuguese and Spanish have the same origin. On one way we have spanish, and the other we have a second language that derived in two: galician and portuguese (which are very similar).