I think that Anakin should be the same age as Obi-Wan. Sebastian Shaw was clearly cast for that reason.
This means that, with Luke & Leia at about 18-20 years old in ANH, this means that Obi-Wan & Anakin should be roughly in their 40s when Episode III ends. This also means that Anakin & Padme have to be together up to that point for Luke & Leia to be conceived.
You might get away with them being mid-30s and Obi-Wan in ANH being mid-50s.
Any thoughts?