I’ve been thinking that, now that AI makes it possible to convincingly redub scenes, it might be possible to edit the Prequel Trilogy to remove all references to the midi-chlorians while still keeping the Chosen One prophecy intact.

For example, in The Phantom Menace, during the scene where Qui-Gon and Obi-Wan speak before the Jedi Council, you could slightly change Qui-Gon’s dialogue with AI. Instead of saying that Anakin was conceived by the midi-chlorians, he could simply say that Anakin was conceived by the Force. I don’t think that would require a huge change, and it would let you preserve the prophecy without the whole midi-chlorian concept.

As odd as it might sound, I’ve actually seen quite a few people who like the idea of the Chosen One prophecy and Anakin being destined to destroy the Sith and bring balance back to the galaxy, but who really dislike the midi-chlorians. An edit like that could satisfy both camps by keeping the prophecy while completely removing the midi-chlorians from the story.