Eh, I really do think modifying those two shots would be the most seamless way, so the scene keeps moving along. The first guy could be on the right side of a blue hand vat, and the second guy on the left. Palpatine stops speaking completely for like 10-15 seconds, which is perfect for an AI line. Something snarky like: “Your uncle / Skywalker was a most generous donor.”
This would fit seamlessly between the other lines imo: “I made Snoke. I have been every voice, you have ever heard, inside your head. Skywalker was a most generous donor. The First Order was just the beginning. I will give you so much more…”
The double meaning there being that Luke was (arguably) responsible for Kylo’s turn to the dark side, while also being the reason Snoke was able to be created via his unwitting genetic donation.