I like the GTA games, but the targeting system still sucks after three tries, it seriously needs an overhaul. If any of you have played "The Warriors," they need add some of it into the GTA series: the fighting system, breaking into cars, smash and grabs, drug dealing. It all seems to fit into the theme of GTA. Also, using the ability to take cover from fire and return fire would also be nice, ala "Man Hunt".
With the next consoles right here, and around the corner, should be pretty fun to see what they come up with ... although, the series is getting a little old.