Trident, your initial question was alright, though the psychological is often physical in the sense it’s not caused by experience but rather is baked in (which you recognize). And if we’re talking about solely about the latter, the question that follows yours is what difference it makes? That’s a sincere question for you.

Your last question is essentially whether flame would take a pill, were it available, to make the dysphoria go away. Any given person may have a different answer and it’s complicated by the internal sense of identity one has had and the idea that a pill would destroy that, rather than fix something.

Unsurprisingly your examples get in the way. I get what you’re saying but they don’t really support what you’re getting at.