The Doctor is The Doctor - albeit a Gallifreyan - whether young, old, white, black, male, female - or even ginger.
We have seen / been told that Gallifreyans regenerate into a different sex before too - The Corsair or The Master/Missy for example…
Think we will ever see a male Romana or Rani?
Fred? Yes, why not?
huh?
Romanadvoratrelundar seemed to be too long a name when she introduced herself to the Doctor. He had trouble pronouncing the full name, and quickly shortened it to “Romana”, though given the choice of being called “Romana” or “Fred” she told him to call her “Fred”.
So yes, Fred. Why not?