Looked the chapter up online (http://www.wenovel.com/book/1500/44197.html) and there are some lines that could be relevant to TLJ.

‘You see,’ he said, still looking down at his bandages, ‘when one’s young, it seems very easy to distinguish between right and wrong, but as one gets older it becomes more difficult. At school it’s easy to pick out one’s own villains and heroes and one grows up wanting to be a hero and kill the villains.’

…

'For those two jobs I was awarded a Double O number in the Service. Felt pretty clever and got a reputation for being good and tough. A double O number in our Service means you’ve had to kill a chap in cold blood in the course of some job.
‘Now,’ he looked up again at Mathis, 'that’s all very fine. The hero kills two villains, but when the hero Le Chiffre starts to kill the villain Bond and the villain Bond knows he isn’t a villain at all, you see the other side of the medal. The villains and heroes get all mixed up.

…

History is moving pretty quickly these days and the heroes and villains keep on changing parts.

Could be hinting that morality in TLJ won’t be so black and white. Or I could be completely off-base and this has nothing to do with Casino Royale.