If you scream at the top of your voice in a Church for fun it’s an offensive and probably breaks some kind of civil law.

If you make the same disruption because of a gallstone it’s not your fault. You need medical attention and probably a stay in hospital.

If you make the same disruption because of schizophrenia it’s not your fault. You may need medical attention and possibly a stay in hospital.

The brain is an organ of the body. The mind is an emergent property of the body.
An unwell mind or damaged brain is no different from an unwell gall bladder or a broken arm.